A Historical Perspective on Evidence-Based Immunology focuses
on the results of hypothesis-driven, controlled scientific experiments
that have led to the current understanding of immunological principles.
The text helps beginning students in biomedical disciplines understand
the basis of immunologic knowledge, while also helping more advanced
students gain further insights.
The book serves as a crucial
reference for researchers studying the evolution of ideas and scientific
methods, including fundamental insights on immunologic tolerance,
interactions of lymphocytes with antigen TCR and BCR, the generation of
diversity and mechanism of tolerance of T cells and B cells, the first
cytokines, the concept of autoimmunity, the identification of NK cells
as a unique cell type, the structure of antibody molecules and
identification of Fab and Fc regions, and dendritic cell